Feature | Details |
---|---|
Name | Sildigra |
Active Ingredient | Sildenafil |
Dosage Forms | 50 mg, 100 mg, 150 mg, 200 mg |
Route of Administration | Oral |
Indications | Erectile Dysfunction |
Onset of Action | 30 to 60 minutes |
Duration | Up to 4 hours |
Visit the Sildigra Site |
Pharmacokinetics of Sildigra
Sildigra is an oral medication, containing the active ingredient sildenafil. It falls under the category of PDE5 inhibitors. The drug demonstrates swift absorption into the bloodstream post-administration. The peak plasma concentrations occur within an hour after ingestion.
Sildenafil 100 mg undergoes hepatic metabolism, mainly through cytochrome P450 enzymes. This results in its major circulating metabolite, which possesses pharmacological activity comparable to sildenafil itself. Both parent compound and metabolite are eventually excreted predominantly through feces, with renal clearance accounting for a smaller fraction.
Its bioavailability is affected by food intake. A high-fat meal can delay the absorption rate, leading to a decreased plasma concentration peak. Despite this, the extent of absorption remains unaffected. Sildigra offers a reliable option for patients dealing with erectile dysfunction.
Dosage Information for Sildigra
Standard dosage varies based on the patient’s condition and tolerance. For most adults, the recommended initial dose is Sildigra 50 mg, taken approximately one hour before sexual activity. Depending on efficacy and tolerability, the dosage may be increased to a maximum of 100 mg or decreased to 25 mg.
The medication should not be consumed more than once daily. Special consideration is given to patients with certain medical conditions. In such cases, dosage adjustments are essential. The age of the patient may also influence the prescribed amount. Lower doses are typically advised for older adults.
It is crucial for users to adhere to their prescribed regimen. Any deviations could reduce efficacy or increase the risk of adverse effects. Patients are encouraged to consult healthcare providers for personalized dosage recommendations.
Warnings and Precautions
Sildigra is contraindicated in individuals with known hypersensitivity to sildenafil. Patients with cardiovascular issues should exercise caution. The medication can exacerbate certain heart conditions.
Concurrent use with nitrates or nitric oxide donors is prohibited. This combination may lead to a severe drop in blood pressure. Patients should inform healthcare professionals about all concurrent medications and supplements.
Those with conditions such as severe liver impairment or rare inherited eye diseases should avoid Sildigra. Professional guidance is advised for individuals with a history of priapism or penile anatomical deformities.
Addressing Missed Doses
Since Sildigra is taken as needed, missing a dose is less common. If a dose is skipped, patients should continue with their regular schedule. Doubling doses to compensate for missed ones is discouraged.
Regular users should consult healthcare providers if they experience consistent difficulty maintaining their prescribed schedule. Proper guidance can assist in maintaining the medication’s efficacy.
Toxicity and Adverse Effects
Exceeding recommended dosages can lead to adverse effects. Symptoms of overdose include severe dizziness, vision changes, and prolonged erections. Immediate medical attention is necessary if overdose is suspected.
Common side effects encompass headache, flushing, and upset stomach. Rarely, serious adverse reactions such as sudden hearing loss or heart attack occur. Patients are advised to discontinue use and seek medical intervention if severe reactions arise.
Where to Buy Sildigra Online
Sildigra is available through several licensed online pharmacies. It is crucial to purchase from reputable sources. Consumers should verify the authenticity of the pharmacy and ensure it is accredited.
Comparing prices and checking for customer reviews can aid in making informed decisions. Patients should avoid unverified sources that offer significantly lower prices, as these may dispense counterfeit products.
Consulting healthcare providers before purchasing online is advisable. Professional advice can help navigate options and ensure safe, effective use of Sildigra.
Data source:
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